Of course, you can set various keyboard shortcuts to take these shots with a simple key combination instead of having to mess about with the mouse. In addition, you can configure the program to take timed shots at regular intervals of several seconds (or minutes).
You also have lots of possibilities when it comes to saving your shots. You can choose the format or image quality you want so it fills more or less space in your folders.
ScreenSnag capture is a tool which you can use to quickly save lots of images from your PC in seconds.